July 6th, 2024

GLP-1 Drugs Like Wegovy, Ozempic Potentially Linked to Blinding Disease

A study suggests a potential link between GLP-1 drugs like semaglutide and a rare blinding disease called NAION in patients with diabetes or obesity. Further research is needed to clarify this association.

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GLP-1 Drugs Like Wegovy, Ozempic Potentially Linked to Blinding Disease

A recent study suggests a potential link between the GLP-1 drugs semaglutide, found in Ozempic and Wegovy, and a rare blinding disease called non-arteritic anterior ischemic optic neuropathy (NAION). The research indicates that patients with type 2 diabetes or obesity who take semaglutide may have an increased risk of developing NAION compared to those on non-GLP-1 medications. However, the study does not establish a direct causal relationship between the drug and the condition. Experts emphasize the need for further research to better understand this association. NAION is a rare condition causing sudden blindness in one eye due to reduced blood flow to the optic nerve. Patients and healthcare providers are advised to weigh the risks and benefits of medications like semaglutide based on individual circumstances and medical history. While the findings are significant, they do not definitively prove a danger associated with these drugs, highlighting the importance of ongoing monitoring and research in this area.

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A study links Ozempic and Wegovy to increased risk of rare blindness (NAION) in diabetes and obesity patients. While causation isn't confirmed, caution and consultation with healthcare providers are advised. Novo Nordisk prioritizes patient safety.

Link Icon 3 comments
By @pknomad - 3 months
Non-causal link but 8x times the risk off of one study at MGH seems to be the eli5.

I made my comment about dependency on these class of drugs a while ago on hacker news but I’d love to see a regimented system that helps patients eventually get off of these drugs or otherwise it seems like we’re trading one con for another (albeit much lesser).

By @marvel_boy - 3 months
The condition, known as non-arteritic anterior ischemic optic neuropathy (NAION), causes sudden blindness due to a lack of blood flow to the optic nerve.