52,000-year-old woolly mammoth chromosomes reconstructed from 'jerky-like' skin

Researchers have reconstructed the 52,000-year-old woolly mammoth genome from a remarkably well-preserved specimen found in Siberia. Using a new technique called Hi-C, scientists analyzed the 3D structures of the mammoth genome for the first time, revealing 28 chromosomes similar to modern elephants. The ancient DNA was so well-preserved that hair follicles and muscle shapes were still intact. This breakthrough provides insights into mammoth genetics, including genes related to cold adaptation and hair growth. The study opens possibilities for studying other extinct species using Hi-C, although finding well-preserved samples like the mammoth remains a challenge. The research also hints at potential applications in de-extinction efforts, with scientists exploring how this technique could help revive ancient species like the mammoth and Tasmanian tiger. While the study showcases the power of Hi-C in ancient DNA analysis, challenges remain in finding suitable samples for further research.