New anti-ageing therapy extends life of mice by 25%
A new anti-ageing therapy, inspired by axolotl salamanders, extends mice lifespan by 25% by inhibiting IL-11. The study in Nature suggests potential benefits for human healthspan and lifespan, pending further trials.
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A new anti-ageing therapy, inspired by the regenerative abilities of axolotl salamanders, has been found to extend the lifespan of mice by 25%. The therapy involves inhibiting a pro-inflammatory protein, IL-11, which is associated with ageing in mice. By blocking IL-11, the mice were protected against various illnesses, metabolic decline, and frailty, leading to an average lifespan extension of 24.9%. The study, published in Nature, also showed a reduction in age-related cancers with IL-11 inhibition. While the research has not yet been tested on humans, the findings suggest potential benefits for increasing both healthspan and lifespan in people. The study's lead researcher, Stuart Cook, expressed confidence in observing positive anti-ageing effects in humans. However, further human trials are needed to validate these findings and address potential challenges in implementing such therapies, including identifying individuals at risk of frailty and regulatory considerations.
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