July 19th, 2024

Where's the Synthetic Blood?

The American Red Cross faced a blood shortage in January 2022 due to decreased donors from COVID-19. Synthetic blood research explores stem cell and mimic methods to improve transfusion efficiency, facing economic challenges. Blood evolution shows progress from whole blood to component therapy for tailored treatments.

Read original articleLink Icon
Where's the Synthetic Blood?

The American Red Cross faced a severe blood shortage in January 2022, exacerbated by a 10% decline in blood donors due to the COVID-19 pandemic. Synthetic blood production is a promising solution to overcome traditional blood transfusion challenges, with two main approaches: the biologists' method using stem cells and the chemists' method creating blood cell mimics. Synthetic blood development faces economic and manufacturing hurdles before widespread use. Understanding blood as a complex system is crucial for successful synthetic blood creation, as all blood components work together for clot formation and immune response. Historical perspectives on blood transfusions highlight the evolution from whole blood transfusions to component therapy, where blood is separated into plasma, red blood cells, and platelets for specific medical needs. Component therapy offers advantages like tailored treatments but also poses challenges such as dilution and volume overload risks. While current blood banking practices ensure safety, they rely on a shrinking donor pool and carry minimal risks of disease transmission. Synthetic blood research aims to address these limitations and revolutionize transfusion medicine.

Related

Building a Pause Button for Biology

Building a Pause Button for Biology

A technology is under development to pause molecular motion in biology, benefiting neuroscience research, organ transplantation, and medical hibernation. Challenges include fast cooling rates and cryoprotective agents. Milestones involve functional preservation demonstrations.

Computer-designed proteins guide stem cells to form blood vessels

Computer-designed proteins guide stem cells to form blood vessels

Researchers at the University of Washington developed computer-designed proteins to guide stem cells in forming blood vessels, showing promise in regenerative medicine for organ repair. The study highlights potential advancements in tissue development research.

Why haven't biologists cured cancer?

Why haven't biologists cured cancer?

Biologists face challenges in curing cancer despite technical advancements. Integration of math in genomics has not led to transformative breakthroughs. Biology's complexity demands rapid experimentation for progress in research and trials.

Scientists create a cell that precludes malignant growth

Scientists create a cell that precludes malignant growth

Scientists at the University of Helsinki developed a cell preventing malignant growth, enhancing therapies for diseases like diabetes. Engineered cells show promise in regulating glucose levels and evading immune rejection, advancing safer cell therapies.

Promised Cures, Tainted Cells: How Cord Blood Banks Mislead Parents

Promised Cures, Tainted Cells: How Cord Blood Banks Mislead Parents

Families invest in cord blood banks for potential cures, but The New York Times investigation reveals low usage and contamination issues. Private banks charge high fees with limited proven benefits, facing rejection in clinical trials. Ethical concerns arise over marketing tactics and lack of substantial medical benefits.

Link Icon 4 comments
By @jmorenoamor - 7 months
Giving blood is one of those easy and rewarding actions that you can do without expecting anything in return. Going voluntarily through a small inconvenience just to give something others need, and doing it without any market involved, money, points, karma, rewards, is a nice human experience to me. Maybe that's just my compensation, but the point is, try it, do it, enjoy the act of helping for free.
By @aaron695 - 7 months
I looked at the evidence and it seemed to me it was not healthy to give blood so I stopped.

I'd be pushing on this hard, it isn't getting better and it'll swing on a dime if general opinion goes badly on the health issue.

I image it's close to impossible to do science on this in the West anymore, the universities are full of Imposters and private industry isn't going to put up with the grief from university Imposters and the general public for the amount this is worth.

Hope that China sees it as a priority. People who support real science need to find a way to support China.