'smart' insulin that responds to changing blood sugar levels in real time
Scientists have developed "smart" insulin that responds to blood sugar changes, potentially reducing injections for type 1 diabetes patients to once a week and improving overall health outcomes.
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Scientists have developed a new type of insulin known as "smart" insulin, which responds to changing blood sugar levels in real-time, potentially transforming treatment for type 1 diabetes. Currently, patients must administer synthetic insulin multiple times a day to manage their blood sugar, which can lead to both physical and mental health challenges. The innovative glucose-responsive insulins (GRIs) activate only when blood sugar levels rise, preventing hyperglycemia, and become inactive when levels drop, avoiding hypoglycemia. This advancement could reduce the need for daily injections to as little as once a week. Funded by the Type 1 Diabetes Grand Challenge, which has allocated £50 million for research, six projects are underway to refine these smart insulins. These projects aim to enhance the speed and precision of insulin action, addressing significant limitations of current therapies. Additionally, one project is exploring a combined formulation of insulin and glucagon to stabilize blood glucose levels more effectively. Experts believe that successful development of these smart insulins could significantly alleviate the daily management burden for individuals with type 1 diabetes and improve their overall health outcomes.
- Smart insulin could reduce the frequency of injections for type 1 diabetes patients to once a week.
- Glucose-responsive insulins activate only when needed, preventing both high and low blood sugar levels.
- Six research projects are funded to enhance the development of smart insulins.
- The advancements aim to mimic the body's natural insulin response more closely.
- Successful implementation could revolutionize diabetes management and improve patients' quality of life.
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3 commentsWhenever an article about T1D includes mention of an uncertain and unspecified future date, it’s relatively safe to replace it with “never.”
As someone with T1D, I won’t be holding my breath waiting for this. Personally I’m quite satisfied with multiple daily injections.
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