August 17th, 2024

Uterus transplant trial ends with bundles of joy

A clinical trial in the U.S. showed 14 of 20 women successfully gave birth after uterus transplants, with no congenital abnormalities, but highlighted risks, costs, and immunosuppression concerns.

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Uterus transplant trial ends with bundles of joy

A recent clinical trial in the U.S. involving 20 women who received uterus transplants has demonstrated the feasibility of the procedure, with 14 participants successfully giving birth. Conducted at Baylor University Medical Center, the study found that all 16 babies born from these transplants showed no congenital abnormalities, although some recipients experienced early miscarriages. The trial highlighted the risks associated with the surgeries for both donors and recipients, with complications noted in some cases. Of the 20 participants, six experienced graft failures shortly after the transplant. The researchers noted that while the success rate of live births indicates that transplanted uteri can function comparably to native uteri, the high costs associated with the procedure may limit its accessibility. Additionally, all recipients required immunosuppression to accept the donated organs, raising concerns about the long-term effects of such treatment. The study concludes that while uterus transplants are technically viable, the associated risks and costs need to be addressed for broader application.

- Uterus transplant trial involved 20 women, with 14 achieving live births.

- No congenital abnormalities were found in the babies born from transplanted uteri.

- Complications were reported in some surgeries, but no severe long-term effects were noted.

- The success rate suggests transplanted uteri can function similarly to native ones.

- High costs and long-term immunosuppression effects pose challenges for wider adoption.

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Link Icon 1 comments
By @yieldcrv - 8 months
wow, congratulations, this article shows it to be a complicated process with lots of various frictions to manage. I’m curious if this approach will garner more research to reduce these frictions, or if a different branch of development to incubate a fetus will take hold first.