August 19th, 2024

Objective Bayesian Hypothesis Testing

The article discusses Objective Bayesian Hypothesis Testing, critiques P-values, introduces expected encompassing intrinsic Bayes factors (EEIBFs) as a reliable alternative, and emphasizes the need for better statistical education.

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Objective Bayesian Hypothesis Testing

The article discusses the concept of Objective Bayesian Hypothesis Testing, emphasizing the importance of deriving posterior probabilities for hypotheses using default Bayes factors. It highlights the historical context of hypothesis testing, referencing the clinical trials conducted by Cushny and Peebles at Kalamazoo Psychiatric Hospital, which aimed to evaluate the effectiveness of different soporifics. The text critiques the common reliance on P-values in hypothesis testing, pointing out the frequent misunderstanding that P-values indicate the probability of the null hypothesis being true. It cites examples of misinterpretation, including the "P value fallacy," and discusses the limitations of traditional significance testing. The article introduces the concept of expected encompassing intrinsic Bayes factors (EEIBFs) as a more reliable method for hypothesis testing, providing a framework for calculating posterior probabilities under objective priors. An example using the data from the hyoscine trial illustrates how to apply EEIBFs to compare the effectiveness of two drugs. The article concludes by discussing the foundational role of Bayes factors and objective priors in Bayesian hypothesis testing, contrasting them with traditional methods and emphasizing the need for better statistical education on these topics.

- Objective Bayesian Hypothesis Testing offers a framework for deriving posterior probabilities using Bayes factors.

- The article critiques the common use of P-values, highlighting frequent misunderstandings about their interpretation.

- Expected encompassing intrinsic Bayes factors (EEIBFs) are proposed as a more reliable alternative for hypothesis testing.

- The historical context of hypothesis testing is illustrated through the clinical trials of Cushny and Peebles.

- The importance of proper statistical education on Bayesian methods is emphasized.

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By @underlines - 8 months
A great question that I came across in Hypothesis Driven Development a long time ago: Should you use Frequentist Statistics or Bayesian Statistics? It's relevant when you do A/B or Multivariate Testing.

As it was very difficult for someone like me without higher stats or math education, I can highly recommend the following additional sources:

- https://www.redjournal.org/article/S0360-3016(21)03256-9/ful...

- https://amplitude.com/blog/frequentist-vs-bayesian-statistic...

- https://indico.cern.ch/event/568904/contributions/2651065/at...

By @vcdimension - 8 months
This article is very interesting and informative, however it's a bit ironic that an article about misinterpretations of the meaning of the p-value, misinterprets the misinterpretation; in the first blue box it's clear that Bernstein is interpreting the p-value as the probability of randomly rejecting the null (which is what you do when you get something statistically significant) yet in the text following that they say he's interpreting it as the probability of the null. Bernsteins mistake is that he appears to interpret it as an unconditional probability rather than a conditional one (correct interpretation; p-value = Prob(rejecting the null when the null is true)).
By @elmomle - 8 months
When the author says "objective" they are referring to a prior that gives equal weight to values within the null hypothesis and to those without (along with a few other things: symmetric and non-increasing away from the mean). I appreciate this approach, and think there's much to commend it, but think that that's a key thing to be aware of (because any use of "objective" when referring to priors is, shall we say, dubious).
By @bookofjoe - 8 months
Off topic but topical: Mike Lynch's yacht was named "Bayesian"