June 27th, 2024

Tardigrade genes edited with an advanced CRISPR technique

Researchers at the University of Tokyo used DIPA-CRISPR to edit tardigrade genes, aiming to understand resilience mechanisms. This technique could have medical applications, like preserving human organs. The study reveals tardigrades' genetic traits.

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Tardigrade genes edited with an advanced CRISPR technique

Researchers at the University of Tokyo have successfully edited the genes of tardigrades using an advanced CRISPR technique called DIPA-CRISPR. Tardigrades, also known as "water bears" or "moss piglets," are microscopic animals known for their resilience in extreme conditions. The study, published in PLOS Genetics, marks the first time this technique has been applied to non-insect organisms. By editing the genes of a tolerant species of tardigrade, scientists aim to understand the genetic basis for surviving harsh environments. The method used, DIPA-CRISPR, allows for precise gene editing in tardigrade offspring, potentially leading to medical applications, including exploring the possibility of dehydrating and rehydrating human organs without degradation. The study's findings shed light on the genetic traits of tardigrades and their potential for scientific and medical advancements, showcasing the unique abilities of these remarkable creatures.

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