Effect of Vitamin C on S. mutans from patients with dental caries (2020)
A study found vitamin C inhibits Streptococcus mutans growth and biofilm formation, suggesting its potential as an anti-cariogenic agent. Further research is required to confirm these results for caries prevention.
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A study investigated the impact of vitamin C on the growth and biofilm-forming potential of Streptococcus mutans, a bacterium associated with dental caries. The research aimed to determine the minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and biofilm prevention concentration (BPC) of vitamin C against S. mutans. Results showed a concentration-dependent inhibitory effect of vitamin C on all tested strains, with average MIC, MBC, and BPC values of 9.38, 10.16, and 5.61 mg/ml, respectively. Vitamin C reduced biofilm formation significantly and exhibited a larger inhibitory zone compared to gentamicin. The study suggests that vitamin C negatively affects S. mutans growth and biofilm formation, potentially paving the way for its repurposing as an anti-cariogenic agent. Further research is needed to solidify these findings. Dental caries, a prevalent condition globally, is often linked to S. mutans biofilm formation, emphasizing the importance of exploring novel approaches, such as vitamin C, for caries prevention.
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