July 2nd, 2024

Alzheimer's scientist indicted for allegedly falsifying data in $16M scheme

An Alzheimer's researcher indicted for falsifying data to secure $16 million in funding. Collaboration with Cassava Sciences on Simufilam treatment. Concerns about research integrity, retractions, FDA inspection, and potential prison time. Cassava acknowledges limited involvement, trials ongoing with 1,800+ patients.

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Alzheimer's scientist indicted for allegedly falsifying data in $16M scheme

An Alzheimer's researcher, Hoau-Yan Wang, has been indicted for allegedly falsifying data to secure $16 million in federal research funding for the development of an Alzheimer's drug and diagnostic test. Wang collaborated with Cassava Sciences, contributing to the scientific basis of their Alzheimer's treatment, Simufilam, currently in Phase III trials. Concerns about Wang's research integrity arose from an internal investigation at the City University of New York, where evidence of scientific misconduct was found. Retractions of Wang's articles and FDA inspection of his analytical work further raised doubts. The indictment accuses Wang of manipulating data and images to deceive the National Institutes of Health. If convicted, Wang faces significant prison time. Cassava acknowledged Wang's indictment, clarifying his limited involvement in their Phase III trials. Despite calls to halt the trials, they continue with over 1,800 patients involved.

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By @laborcontract - 4 months
I know in a lot of past submissions here about academic fraud, a good chunk of the comments wondered how it wasn't a punishable crime.

Well, now we know the answer! I hope we get a lot more of this. Given how much of academic funding is provided by the government, it's not unrealistic to think that the feds can break the back of academic fraud by pursuing more of these cases.

The burden these people cast on society is arguably worse than a ponzi schemer. They steal money from taxpayers, the livelihoods of researchers, and time from those who can least afford to waste it.

By @eigenvalue - 4 months
Would be ironic if the trial shows that the drug works after all this. But that seems incredibly doubtful. This guy should go to prison for a long time. That’s 1,800 people in a trial who could have been taking a non fraudulent drug that has a better chance of working.
By @isaacfrond - 4 months
Well, that's about time. Although, I'm pessimistic that the law can stem the current tide of research fraud, at least it's something.
By @ChrisArchitect - 4 months
By @mensetmanusman - 4 months
Not giving academics FU money is going to backfire.