July 15th, 2024

Scientists make DNA discovery that could help find pancreatic cancer cure

Scientists discover pancreatic cancer deactivates crucial genes, aiding rapid growth. Study reveals DNA methylation silences HNF4A gene, essential for organ function. Research offers hope for new treatments, funded by Pancreatic Cancer UK.

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Scientists make DNA discovery that could help find pancreatic cancer cure

Scientists have made a significant DNA discovery related to pancreatic cancer, a disease with one of the worst survival rates among common cancers. Researchers from the UK and US found that pancreatic cancer can deactivate molecules in crucial genes, aiding the rapid growth and spread of the disease. Pancreatic cancer is diagnosed in over half a million people annually and has poor survival rates. The discovery offers hope for new treatments by shedding light on how the cancer behaves and spreads. The study revealed that pancreatic cancer triggers DNA methylation, silencing molecules in the HNF4A gene, which is essential for organ function. This finding could lead to potential new treatments in the future. Pancreatic cancer is often diagnosed late, limiting treatment options and resulting in a high mortality rate. The research, funded by Pancreatic Cancer UK, aims to improve understanding of the disease's aggressiveness to develop more effective treatments.

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By @01100011 - 9 months
They list Steve Jobs as dying from pancreatic cancer but that's not really correct as it was a different type than the aggressive cancer for which the advancement was made.

Steve had an islet cell neuroendocrine cancer which is much more rare.