July 31st, 2024

Two new dementia risks identified by major report

A Lancet Commission report identifies failing eyesight and high cholesterol as new dementia risk factors, suggesting that addressing 14 health issues could prevent nearly half of global cases by 2050.

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Two new dementia risks identified by major report

A major report by the Lancet Commission has identified two new risk factors for dementia: failing eyesight and high cholesterol. The report highlights that addressing 14 health issues could potentially prevent nearly half of dementia cases globally, with middle-aged individuals and those in poorer countries benefiting the most. It predicts that the number of people living with dementia could exceed 153 million by 2050. The report emphasizes that while genetics play a significant role in dementia risk, approximately 45% of the risk can be modified through lifestyle changes. Recommendations include improving access to hearing aids, ensuring quality education, promoting physical activity, managing high blood pressure and cholesterol, addressing obesity, reducing social isolation, and screening for vision problems. The report also notes that hearing loss and high cholesterol are linked to the highest percentages of preventable dementia cases. Experts caution that while lifestyle changes can enhance brain resilience, they cannot guarantee prevention, as many risk factors are beyond individual control. The report's findings are seen as groundbreaking, challenging the notion that dementia is an inevitable part of aging. It suggests that vision loss may contribute to dementia by limiting social engagement and experiences. Despite rising dementia cases in low-income countries due to increased life expectancy, there has been a decline in dementia rates in high-income countries, attributed to healthier lifestyles. The report encourages proactive measures to mitigate dementia risk at any age.

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Link Icon 6 comments
By @roughly - 3 months
It's interesting to look at the list of factors from the article - there's an obvious set of physical factors (obesity, cholesterol, smoking, etc), and then there's things like hearing loss, social isolation, and now visual loss, that all seem to be associated with less input to the brain or less informational processing. There's also the studies around staying cognitively active - my understanding is a lot of that is building additional capacity so the effects of dementia & Alzheimers are less noticeable, but it's interesting to see this kind of almost "hardware/software" split in the risk factors.

Depression is an interesting one because it's so multicausal that I'd almost wonder if it's a comorbidity, rather than a risk factor.

By @sien - 3 months
For anyone who wants to help do something about dementia, at least in a tiny way, and is perhaps concerned about their own risk of dementia there is a pretty easy way you can contribute.

The UCSH Brain Health Registry :

https://www.brainhealthregistry.org

You can register and every few months you answer some questions about yourself and do some fairly basic mental health tests.

By @Archelaos - 3 months
Is this based on an intervention study or were they just looking for correlations?
By @musha68k - 3 months
Let's not forget viruses like Covid which is still wreaking havoc on our brains.

Danielle Beckman is not only researching this space but trying to make us more aware:

https://ucdavis.app.box.com/s/6stuakg87dvmhjhkmg2j9219sou28u...

https://www.daniellebeckman.com/projects-8

https://x.com/danibeckman

By @chaostheory - 3 months
I’m surprised poor sleep isn’t on the list.
By @fxtentacle - 3 months
failing eyesight and high cholesterol

I hate those headlines that could easily be informative but instead are optimised for clicks.