August 10th, 2024

Ancient DNA Revolution

Advancements in archaeogenetics are enhancing our understanding of ancient human history, with over 10,000 genomes sequenced, including Neanderthal and Denisovan, revealing insights into migration and domestication.

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Ancient DNA Revolution

The article discusses the advancements in the field of archaeogenetics, which is revolutionizing our understanding of ancient human history through the study of ancient DNA. Despite the challenges posed by the degradation and fragmentation of ancient DNA, researchers have made significant strides, including the successful mapping of the Neanderthal genome in 2010 and the recent sequencing of a 200,000-year-old Denisovan genome. Over the past decade, scientists have sequenced the genomes of over 10,000 ancient individuals, revealing insights into human migration, animal domestication, and ancient ecosystems. Innovative extraction and analysis techniques have allowed for the recovery of genetic material from diverse archaeological contexts, including soil samples. This research is shedding light on various historical topics, such as the population dynamics of the Roman Empire and the genetic lineage of ancient domesticated animals. The ongoing developments in archaeogenetics promise to further enhance our understanding of the past and the connections between ancient and modern populations.

- The field of archaeogenetics is rapidly evolving, providing new insights into ancient human history.

- Significant achievements include the mapping of the Neanderthal genome and the sequencing of a Denisovan genome.

- Researchers have sequenced over 10,000 ancient genomes in the last decade.

- New techniques allow for the extraction of DNA from a variety of archaeological sources.

- The research has implications for understanding human migration, domestication, and ancient ecosystems.

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Link Icon 3 comments
By @abe94 - 4 months
I've been following this field closely for the last 5 years, its really cool what we can learn about our own ancestry now!

For those interested in a good overview David Reich's book is still excellent - https://en.wikipedia.org/wiki/Who_We_Are_and_How_We_Got_Here

And if you're interested in an in-depth ancestry analysis of your dna you can use commercial options like https://illustrativedna.com/ or analyse your dna yourself with qpadm https://uqrmaie1.github.io/admixtools/articles/qpadm.html

By @epgui - 4 months
For people interested in publicly traded companies (this is not investment advice and I am not qualified whatsoever) that make this possible: NASDAQ:PACB and LSE:ONT.

To the best of my knowledge, ILMN and other similar short-read sequencing technologies are not able to perform to the level required for these sorts of applications.