China bans clinical research in germline genome editing as 'irresponsible'
China bans clinical research on germline genome editing due to ethical concerns, following He Jiankui's controversial gene-editing of babies. The new guideline stresses ethical considerations and prohibits heritable changes in DNA. Other countries have similar restrictions.
Read original articleChina has recently banned all clinical research involving germline genome editing, citing it as irresponsible. The new ethics guideline released by China's Ministry of Science and Technology prohibits any clinical research that involves altering the DNA in sperm, eggs, or early embryos to introduce heritable changes. This move comes after the controversial case of He Jiankui, who created the world's first gene-edited babies in 2018. The guideline emphasizes the importance of understanding the benefits, risks, and alternative options before considering clinical research under strict supervision. It strictly prohibits the use of genome editing on germ cells, fertilized eggs, or human embryos for reproductive purposes due to unpredictable risks. The guideline also highlights the need for ethical considerations in human genome editing research, as it can have significant impacts on society. China has been tightening regulations on genome editing research since He's case, with a focus on ethical governance and risk monitoring in science and technology. Other countries like Britain, Canada, Australia, and South Korea have similar laws banning research into human genome editing for reproductive purposes.
Related
New technique opens the door to large-scale DNA editing to cure diseases
Researchers have described a new genetic editing mechanism using jumping genes to insert DNA sequences accurately. This system shows promise in overcoming CRISPR limitations, with 94% accuracy and 60% efficiency in bacteria. Optimizations are needed for mammalian cell use.
Trying to outrun her disease, researcher creates powerful epigenetic editor
A powerful epigenetic editor developed by researchers at the Broad Institute aims to combat prion disease, a rare neurodegenerative condition. The tool utilizes CRISPR gene editing to potentially treat this fatal disease.
Scientists create a cell that precludes malignant growth
Scientists at the University of Helsinki developed a cell preventing malignant growth, enhancing therapies for diseases like diabetes. Engineered cells show promise in regulating glucose levels and evading immune rejection, advancing safer cell therapies.
One man's DNA became a pillar of genetics
The Human Genome Project used DNA from donor RP11 extensively, raising ethical concerns about consent and privacy. Despite deviations from initial promises, the project's genome remains crucial for genetics research, highlighting ethical challenges in scientific endeavors.
Scientists Say New Gene Editing Tool Is Like a 'Word Processor' for DNA
Scientists have developed a new gene editing tool, similar to a "word processor" for DNA, called bridge editing or seekRNA. It offers precise modifications without breaking DNA strands, potentially surpassing CRISPR's capabilities. This tool requires fewer molecules, making it easier to deliver into cells and handle longer DNA sequences. Researchers aim to adapt it for mammalian cells, revolutionizing gene therapy and synthetic biology.
Related
New technique opens the door to large-scale DNA editing to cure diseases
Researchers have described a new genetic editing mechanism using jumping genes to insert DNA sequences accurately. This system shows promise in overcoming CRISPR limitations, with 94% accuracy and 60% efficiency in bacteria. Optimizations are needed for mammalian cell use.
Trying to outrun her disease, researcher creates powerful epigenetic editor
A powerful epigenetic editor developed by researchers at the Broad Institute aims to combat prion disease, a rare neurodegenerative condition. The tool utilizes CRISPR gene editing to potentially treat this fatal disease.
Scientists create a cell that precludes malignant growth
Scientists at the University of Helsinki developed a cell preventing malignant growth, enhancing therapies for diseases like diabetes. Engineered cells show promise in regulating glucose levels and evading immune rejection, advancing safer cell therapies.
One man's DNA became a pillar of genetics
The Human Genome Project used DNA from donor RP11 extensively, raising ethical concerns about consent and privacy. Despite deviations from initial promises, the project's genome remains crucial for genetics research, highlighting ethical challenges in scientific endeavors.
Scientists Say New Gene Editing Tool Is Like a 'Word Processor' for DNA
Scientists have developed a new gene editing tool, similar to a "word processor" for DNA, called bridge editing or seekRNA. It offers precise modifications without breaking DNA strands, potentially surpassing CRISPR's capabilities. This tool requires fewer molecules, making it easier to deliver into cells and handle longer DNA sequences. Researchers aim to adapt it for mammalian cells, revolutionizing gene therapy and synthetic biology.