July 13th, 2024

Scientists Say New Gene Editing Tool Is Like a 'Word Processor' for DNA

Scientists have developed a new gene editing tool, similar to a "word processor" for DNA, called bridge editing or seekRNA. It offers precise modifications without breaking DNA strands, potentially surpassing CRISPR's capabilities. This tool requires fewer molecules, making it easier to deliver into cells and handle longer DNA sequences. Researchers aim to adapt it for mammalian cells, revolutionizing gene therapy and synthetic biology.

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Scientists Say New Gene Editing Tool Is Like a 'Word Processor' for DNA

Scientists have discovered a new gene editing tool that resembles a "word processor" for DNA, potentially surpassing the capabilities of CRISPR. This new tool, found in bacterial "jumping genes," allows for precise modifications to DNA sequences without breaking the DNA strands or relying on cell repair mechanisms. The system, termed bridge editing or seekRNA, can cut, paste, and flip any DNA sequence, offering a safer and more efficient alternative to CRISPR. Unlike CRISPR, this tool requires fewer and smaller molecules, making it easier to deliver into cells and capable of handling longer DNA sequences. While the tool has shown promise in bacteria, researchers aim to adapt it for use in mammalian cells. If successful, this new gene editing system could revolutionize gene therapy and synthetic biology, offering a powerful and versatile approach to genetic modifications.

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By @hulitu - 3 months
> Scientists Say New Gene Editing Tool Is Like a 'Word Processor' for DNA

So they still need an Excel and a Powerpoint for DNA to have something useful. /s