PFAS can be absorbed through human skin

Recent research from the University of Birmingham has revealed that per- and polyfluoroalkyl substances (PFAS), commonly known as "forever chemicals," can be absorbed through human skin, challenging previous assumptions that skin acts as a barrier to these substances. PFAS are persistent chemicals found in various consumer products, including cosmetics and waterproof clothing, and have been detected globally, including in human blood and breast milk. The study utilized 3D models of lab-grown human skin to investigate the dermal absorption of 17 different PFAS chemicals. Results indicated that short-chain PFAS were absorbed more readily than long-chain variants, with 58% of perfluoropentanoic acid absorbed after 36 hours, compared to only 13% for perfluorooctanoic acid (PFOA). The findings suggest that dermal exposure could be a significant pathway for PFAS entry into the human body, particularly given the frequent contact with products containing these chemicals. The study highlights potential health risks associated with PFAS, including hormone disruption, lowered immune response to vaccinations, and increased cancer risk. As industries shift towards shorter-chain PFAS, which are perceived as less toxic, the research raises concerns about the increased absorption of these compounds through the skin. The authors emphasize the need for manufacturers and regulators to assess the risks of PFAS-containing products before they reach the market, given the implications for human health and safety.