Research finds link between prenatal exposure to plastics and autism in boys
Florey researchers found a link between prenatal BPA exposure and autism in boys, suggesting BPA disrupts brain development. A fatty acid may help mitigate these effects, influencing public safety regulations.
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Florey researchers have identified a potential link between prenatal exposure to bisphenol A (BPA), a common plastic chemical, and autism in boys. The study, published in Nature Communications, analyzed urine samples from pregnant women and found higher BPA levels in those who later gave birth to sons diagnosed with autism. The research focused on two large birth cohorts: the Barwon Infant Study in Australia and the Columbia Centre for Children’s Health and Environment in the USA. The findings suggest that BPA disrupts hormone-controlled brain development in male fetuses by silencing the aromatase enzyme, which is crucial for converting testosterone to neuroestrogen. Boys with lower aromatase levels and higher maternal BPA exposure were found to be significantly more likely to exhibit autism symptoms and receive a diagnosis. The study also explored potential interventions, noting that a fatty acid called 10-hydroxy-2-decenoic acid showed promise in reversing autism-like characteristics in mice exposed to BPA. These findings are expected to inform public safety regulations regarding chemical exposure during pregnancy and early life.
- Higher BPA levels in pregnant women are associated with autism in their sons.
- BPA disrupts hormone-related brain development by affecting the aromatase enzyme.
- Boys with lower aromatase levels are at greater risk for autism when exposed to BPA.
- A fatty acid shows potential for mitigating BPA's adverse effects in animal studies.
- Research findings may influence public safety recommendations on chemical exposure.
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4 commentsIf the link between BPA and autism is confirmed, it could be reasonable to have a closer look at other xenoestrogens (like DDT, still not banned in some SEA countries, or zeranol).
Many software engineers can be found in this group as having enhanced spatial visualization skills is a perfect fit for coding.
Or do people still want to “cure” people who are different ?
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