August 15th, 2024

Low magnesium levels increase disease risk, new study shows

A University of South Australia study links low magnesium levels to increased DNA damage and chronic diseases, emphasizing the need for adequate intake to mitigate health risks and support cellular health.

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Low magnesium levels increase disease risk, new study shows

A recent study from the University of South Australia highlights the critical role of magnesium in health, linking low magnesium levels to an increased risk of DNA damage and various chronic diseases. Researchers analyzed blood samples from 172 middle-aged adults and found a significant correlation between low magnesium and elevated levels of homocysteine, a genotoxic amino acid. This combination is associated with a higher susceptibility to diseases such as Alzheimer's, Parkinson's, gastrointestinal disorders, certain cancers, and diabetes. The study emphasizes that a daily magnesium intake below 300mg can lead to health risks, particularly in relation to DNA integrity. The findings indicate that maintaining adequate magnesium levels is essential for protecting genes from the toxic effects of homocysteine, especially when folate and vitamin B12 levels are low. The researchers suggest that chronic magnesium deficiency may impair energy production and accelerate tissue aging, increasing the likelihood of early disease onset. The study calls for further research to determine optimal magnesium intake levels through diet or supplements and their potential impact on cancer and other chronic diseases. The results have been published in the European Journal of Nutrition.

- Low magnesium levels are linked to increased DNA damage and chronic disease risk.

- A daily intake of less than 300mg of magnesium can elevate health risks.

- Magnesium deficiency is associated with higher levels of homocysteine, which is toxic to DNA.

- Adequate magnesium is crucial for energy production and cellular health.

- Further research is needed to establish optimal magnesium intake for disease prevention.

Link Icon 4 comments
By @apsec112 - 8 months
It doesn't show this! It shows that there's a correlation between low magnesium, and biomarkers which are themselves correlated with disease. But that could mean anything. Maybe foods that are high in magnesium are also more satiating (because junk food doesn't have much magnesium), so people with high magnesium diets also eat less, making them healthier. Or maybe high magnesium foods also tend to have some other chemical X, which has good health effects even though the magnesium doesn't. Or maybe bad health causes the body to absorb magnesium poorly, or to get rid of too much magnesium. We saw this with vitamin D: low vitamin D correlates with everything bad, because people who are sick and unhealthy get less sun. But supplementing vitamin D doesn't fix the badness.
By @teslabox - 8 months
I salvaged some dandelion roots from one of my beds. They're currently bunched together in a plastic pot - I ought to find a place to put them. Dandelions are easy to grow because they grow themselves back from the roots every spring. Dandelion broth is simple to make: chop up the greens, boil them for an hour, then strain the fiber.

Dandelion nutrients: https://fdc.nal.usda.gov/fdc-app.html#/food-details/169226/n...

A magnesium supplement is easy to make with carbonated water and magnesium hydroxide. Purebulk sells powdered magnesium hydroxide, otherwise every grocery store sells this as a liquid laxative in the pharmacy. This pdf has the directions: https://www.afibbers.org/Wallerwater.pdf

By @PaulHoule - 8 months
My experience is that cheap magnesium oxide tablets act like sleeping pills for me and can be too sedating if I take too many. I've also tried more expensive pills that claim to be more bioavailable but I'm not impressed.