Low level of Magnesium linked to disease-causing DNA damage

Magnesium L-Threonate - has the most potent therapeutical effect because it can effortlessly cross blood-brain barrier. The drawback is that some people are sensitive to this form of magnesium, those people can have nausea, vomit, migraines, etc. IMHO, I would advise against everyday use because this form is more a medication than a supplement. It is used for serious conditions like dementia, neurological impairment, nutrimental deficiencies.

Magnesium Taurate - a combination of magnesium and taurine. A good form for people with metabolic conditions: T1DM, T2DM, hyperlipidemia, vitamin and mineral deficiencies.

Magnesium Glycinate (aka Magnesium Bisglycinate) - a bit less potent form of magnesium, but has good bioavailability, fewer side-effects. This form is also a source of glycine which is an important amino acid beneficial for metabolism, has a mild calming and stabilizing effect on nervous system. Helps to cope with anxiety, panic attacks, insomnia.

Magnesium Citrate - a cheaper but ok magnesium form for everyday use.

Magnesium Oxide - the cheapest and the least efficient form of magnesium. Unfortunately, this is the most widespread form in many countries due to its low price. Try to avoid this form if you have a choice.

Bonus point: if you have a specific condition, you can combine several forms of magnesium to reach multiple therapeutic goals. For example, some popular combinations are presented below:

  a. Magnesium Taurate + Magnesium Glycinate
  b. Magnesium L-Threonate + Magnesium Taurate
  c. Magnesium L-Threonate + Magnesium Taurate + Magnesium Glycinate

I’ve gotten ocular migraines since I was about 13, and one day a decade or so ago I noticed one was about to come on and randomly googled something that brought me to magnesium deficiency and migraines. I didn’t give it much thought and just ran out to the corner health food spot and they happened to have a liquid magnesium supplement made by the German company Floradix. I took it and while I still got the ocular migraine, it passed pretty quickly.

I’ve been taking a magnesium supplement pretty much daily since then. The only time I really get an ocular migraine these days is if I’ve run out of supplements and go a week or so without them.

I remember telling a doctor friend of mine about it early on and they were very dismissive about it. Glad people are researching it, I do feel it’s helped in my case.

> Conversely, the study found a positive relationship between high levels of magnesium and those of folate and vitamin B12.

Magnesium is known to be involved in "activating" riboflavin[1] into FMN, which then is involved in "activating" folate and B12 (and B6)[2][3] by transferring the methyl group back and forth to form methylfolate and methylcobalamin. Homocysteine level is often considered a useful measurement of vitamin B12 status.

[1] https://www.uniprot.org/uniprotkb/Q969G6/entry magnesium is also involved in ATP production, zinc is also a cofactor in this reaction

[2] https://lpi.oregonstate.edu/book/export/html/99#:~:text=Ribo....

[3] https://lpi.oregonstate.edu/mic/vitamins/riboflavin

Magnesium bisglycinate supplementation (and vitamin D in winter) has greatly reduced the frequency and intensity of restless legs.

This is pretty well known in the RLS community, so just mentioning it in case anyone here could benefit.

Everybody here is talking about supplements, and I didn't see a single comment about food. So here we go: food that are rich in magnesium: beans, nuts, and seeds, spinach, kale, yogurt, milk, cheese.

Has anybody read this headline and wondered whether it means “not enough Mg” or “even a tiny bit of Mg”?

There are so many different types of magnesium supplements out there, which type of magnesium should people consider?

This is about magnesium lowering homocysteine but homocysteine can be lowered with methylated b vitamin supplementation in people for whom it's elevated.

Magnesium is great, but is it really the best way to lower homocysteine levels? Should be easy to test with standard blood tests.

It also causes excess stress and anxiety and mental health issues.

There are magnesium gummies.

I learned last week of magnesium based pools, as an alternative for chloride or salt pools. It is said to be good for the skin.

Magnesium is one of the most underrated supps

Another source of magnesium (my favorite) is Fiji water.

I doubt supplementing magnesium solves the issues.

Panacea or Magic Bullet Fallacy etc.