September 1st, 2024

The case of the nearly 7k missing pancreases

Nearly 7,000 pancreases from deceased donors in the U.S. went untransplanted from 2021 to 2023, raising concerns about organ utilization and OPO accountability amid regulatory changes.

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The case of the nearly 7k missing pancreases

The issue of unaccounted organ donations, particularly pancreases, has come to light, revealing that nearly 7,000 pancreases removed from deceased donors in the U.S. between 2021 and 2023 were not transplanted. Organ Procurement Organizations (OPOs), which are responsible for collecting organs, have been criticized for underutilizing available organs. A 2019 report estimated that tens of thousands of usable organs, including pancreases, are not used each year, despite a national waitlist exceeding 100,000 people. Recent regulatory changes aimed to improve OPO accountability, but a loophole has emerged. OPOs can classify pancreases as "recovered for research," allowing them to inflate their recovery statistics without actually facilitating transplants. The number of pancreases designated for research surged from 513 in 2020 to 3,238 in 2023, while only 24 actual transplants occurred. This discrepancy raises concerns about the allocation of organs and the effectiveness of OPOs. In response to these issues, the Centers for Medicare and Medicaid Services (CMS) has clarified that only pancreases used in legitimate research will count towards OPO performance metrics, potentially leading to better organ utilization in the future.

- Nearly 7,000 pancreases removed from deceased donors in the U.S. went untransplanted from 2021 to 2023.

- OPOs have been criticized for underutilizing organs, with estimates suggesting tens of thousands of usable organs are not used annually.

- A loophole allows OPOs to classify pancreases as "for research," inflating recovery statistics without actual transplants.

- The number of pancreases designated for research increased significantly, while actual transplants remained low.

- CMS has clarified that only pancreases used in legitimate research will count towards OPO performance metrics.

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Link Icon 2 comments
By @cperciva - 8 months
While I don't doubt that there's a lot of fudging going on here, the author is a bit off in thinking that the only research use of pancreata is in transplanting islet cells into patients. In particular, there has been a lot of research recently into "encapsulated islets" -- placing them inside some form of membrane which allows nutrients in and insulin out, but protects them from the immune system. This would make it possible to implant an "artificial pancreas" without needing life-long immunosuppressant therapy.
By @zaptheimpaler - 8 months
What stands out to me is that private actors figured out a loophole within weeks/months and it took the government 4 years to close it. A familiar story of the sad state of government regulation wherever you look. They treat lawmaking as a waterfall process, trying to plan for every eventuality years into the future and inevitably failing instead of going faster and course-correcting along the way.