September 5th, 2024

Rethinking Exercise: How Too Much Can Speed Up Aging, According to Finnish Study

Recent research from the University of Jyvaskyla suggests excessive exercise may accelerate biological aging, while moderate activity is linked to better health outcomes, emphasizing lifestyle factors over exercise alone.

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Rethinking Exercise: How Too Much Can Speed Up Aging, According to Finnish Study

Recent research from the University of Jyvaskyla in Finland has challenged the conventional wisdom that regular exercise is essential for longevity. Over a 45-year study involving more than 11,000 Finnish twins, findings indicated that excessive physical activity might not only fail to extend lifespan but could also accelerate biological aging. Participants were categorized into four groups based on their activity levels: sedentary, moderately active, active, and highly active. While initially, the least active group showed a 20% higher mortality risk, this difference diminished when accounting for lifestyle factors like education and body mass index. Notably, those engaging in extreme levels of physical activity were found to be biologically older by an average of 1.8 years compared to those with moderate exercise habits. This suggests that the health benefits associated with physical activity may be more related to overall lifestyle rather than exercise alone. Dr. George Savva highlighted the study's robust design but noted the need to consider how physical activity impacts factors like BMI. The World Health Organization continues to recommend 150 to 300 minutes of moderate exercise or 75 to 150 minutes of vigorous exercise weekly as a guideline for healthy living.

- Excessive exercise may accelerate biological aging, according to new research.

- The study involved over 11,000 Finnish twins over a 45-year period.

- Moderate exercise is linked to better health outcomes than extreme physical activity.

- Lifestyle factors significantly influence the relationship between exercise and longevity.

- The World Health Organization recommends specific weekly exercise guidelines for adults.

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Link Icon 15 comments
By @brigadier132 - 6 months
This is a controversial study, apparently what they did to test for how exercise affected aging was they decided to control for "confounding" variables such as high blood pressure, obesity, etc. Except, these aren't confounding variables but mediating variables.

There was actually a youtube video about this very topic that I think is pretty good:

https://www.youtube.com/watch?v=Ic4nUxMYBRk

The takeaway is: If you are not training for marathons or the tour de france you are probably not overexercising to the point of causing negative health outcomes

By @arcanus - 6 months
The study appears to be misrepresented. From the paper at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274991/

"Although biological ageing was accelerated in sedentary and highly active classes, after adjusting for other lifestyle-related factors, the associations mainly attenuated."

"Conclusion: Being active may reflect a healthy phenotype instead of causally reducing mortality."

Therefore, the paper isn't supporting the article claim that too much exercise is speeding up aging, rather, that this is dominated by genetics.

By @prmph - 6 months
By @chiefalchemist - 6 months
> Their findings, which earned a prestigious sports medicine award in Finland, suggest that excessive physical activity might not only be less beneficial for extending lifespan but could also potentially accelerate aging.

The key word is: excessive.

Furthmore, exercise isn't only about quantity (i.e., lifespan), it's about quality (i.e., avoiding health issue compromise quality of life).

Given the choice, running an extra mile is likely a wiser default than drinking an extra Coke.

By @vinni2 - 6 months
> Further intriguing results showed that those at the extremes of physical activity—either too little or too much—experienced accelerated biological aging.

So moderate exercise is the optimal. Not too much or too little. But how does one know what is too much? It is different for different people.

By @throwup238 - 6 months
> Further intriguing results showed that those at the extremes of physical activity—either too little or too much—experienced accelerated biological aging.

If it’s at the extreme end of exercise, chances are the effect can be explained mostly by injury. Especially once someone is elderly, an injury that puts them out of commission for months is often the beginning of the end.

By @bilsbie - 6 months
Another factor to consider is that too much exercise can increase the chance of injuries which can lead to long periods of no exercise.

After 40 my rule of thumb is never do intense exercise two days in a row. Hopefully it helps.

By @helsinkiandrew - 6 months
If I've read it correclty (Table 1 in the report: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274991/#SD1)

Highly Active (C5) appears to be 7-8 metabolic equivalent (MET) hours a day and Active (C4) is 3-4 hours a day.

8 MET hours would be running for an hour at enough pace to be consuming about 600 calories, assuming your consumption at rest is 75 - please correct me if you understand METs better

By @francisofascii - 6 months
I wonder if excessive exercise simply leads to less sleep, thus speeding up aging. If you are trying to run 70 miles a week, hold down a full time job, take care of kids, etc, then you end up stressed out and sleeping less.
By @kif - 6 months
Time and time again, we learn that 'your mileage might vary'. I've found that the best way to live life is to find out what is considered best, and adapt it to you and your body.
By @qgin - 6 months
Just for some context, the highly active group was doing about 8 MET hours per day, which is the equivalent of jogging for about an hour and a half every day at a 10 min mile.
By @tbe-stream - 6 months
It seems strange to correct for BMI differences, since a lower BMI is one of the main ways regular exercise is supposed to improve your health.