Studies suggest a drug-free nasal spray could ward off respiratory infections
Researchers at Brigham and Women’s Hospital developed a drug-free nasal spray, PCANS, which captures and neutralizes respiratory pathogens, showing effectiveness against viruses like influenza and SARS-CoV-2 in preclinical studies.
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Researchers at Brigham and Women’s Hospital have developed a drug-free nasal spray, known as Pathogen Capture and Neutralizing Spray (PCANS), which shows promise in preventing respiratory infections caused by viruses and bacteria. Preclinical studies indicate that PCANS can effectively capture and neutralize pathogens, forming a gel-like barrier in the nasal cavity that immobilizes germs. The spray demonstrated a significant ability to block respiratory droplets, capturing twice as many as mucus alone. In laboratory tests, it neutralized nearly all tested pathogens, including influenza and SARS-CoV-2, and showed exceptional efficacy in mouse models, reducing viral levels in the lungs by over 99.99%. The formulation is based on ingredients recognized as safe by the FDA and has not yet been tested in humans. The researchers emphasize the need for additional protective measures against respiratory diseases, especially in light of ongoing threats like COVID-19 and seasonal influenza. Future studies may also explore the potential of PCANS to alleviate allergies.
- A new drug-free nasal spray could help prevent respiratory infections.
- The spray captures and neutralizes pathogens in the nasal cavity.
- Preclinical studies show it is effective against various viruses, including influenza and SARS-CoV-2.
- The formulation is based on FDA-approved ingredients and has not yet been tested in humans.
- Future research may investigate its potential for allergy relief.
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23 commentsNever thought about using it to block viral infections, but it makes sense: coating the nasal passages with artificial "mucus-like substance" so particles don't reach the membranes. Makes total sense that approach also work for viruses.
https://www.ncbi.nlm.nih.gov/research/coronavirus/publicatio...
I stopped using other kinds of spray since discovering that it fixes my sinus infections in a matter of a day or two.
A certain amount of influenza virus acts as a toxin and just kills you?
I wonder if it feels unpleasant
This is very good engineering imo.
No need to remind me that without this we wouldn’t have all our medical advancements, it’s just a sad footnote to all of modern medicine, that’s all.
Stopped reading there. As promising as it sounds, I'll be a lot more interested when this is a product that's proven to work.
(Joke) Wake me when the human studies are done
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