June 28th, 2024

Omega-3 fatty acids (fish oil) could combat depression

A study suggests omega-3 fatty acids can reduce depression and anxiety symptoms in stressed young mice. Results show improved behavior and molecular changes, but human translation remains uncertain due to study limitations.

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Omega-3 fatty acids (fish oil) could combat depression

A study published in Neurobiology of Stress suggests that omega-3 fatty acids can alleviate symptoms of depression and anxiety in young mice subjected to stress. The research aimed to explore alternative treatments for adolescent depression, a condition on the rise globally. The study involved exposing mice to stress-inducing conditions and providing them with diets containing omega-3 supplements or placebos. Mice treated with omega-3 showed improved behavior, displaying less anxiety and depressive symptoms compared to those on a regular diet. The omega-3 intake led to behavioral changes and a decrease in pro-inflammatory cytokines, indicating potential molecular mechanisms for the observed improvements. However, the study's translation to humans remains uncertain. While the findings are promising, the study acknowledges limitations in applying results from a mouse model directly to humans.

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Link Icon 4 comments
By @rotexo - 5 months
I am honestly very glad for people who took omega-3s and who experienced a benefit. For me, though, next time I’m a mouse and I want to drink more sugar water and stay in the middle of an open box vs. the edges (all that was demonstrated in the article, as far as I can tell), I’ll be sure to take some omega 3s. Until then, I’ll keep taking the prescription antidepressants that actually allowed me to get through a PhD program and hold down a job afterwards.
By @earthlingdavey - 5 months
I find it fascinating that it seems like this works for some (humans) but not others.

n=1 ... a tripple dose of omega-3 capsule gives me a noticalbe improvement in my depression within 24 hours.

By @hilux - 5 months
I could have told them this 15 years ago.